1. Recognition of DNA structure using chiral metal chelates:
Research by Jacqueline K. Barton and Douglas C. Rees,
California Institute of Technology
b. The Crystal Structure of two oligomers of B-DNA with five intercalated molecules
of
&Delta -&alpha -[Rh[(R,R)-Me2trien]phi]3+ is shown on your left.
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Color Intercalated Rh Complexes Lime Green
Intercalation is stereoselective (for the &Delta Isomer), sequence specific (5'-TG(intercalator)CA-3') and regioselective (for the major groove of B-DNA).