Visualizations of Cu(I) and Cu(II) Complexes of the Me6Trien Ligand
and Ligands Related to the BCA and BCS Ligands

Dean Wilcox's group at Dartmouth College use the Me6Trien Ligand to deliver Cu(I) and the BCA and BCS Ligands to compete for Cu(I) during their experiments to measure the thermodynamics of Cu(I) binding to metalloproteins:


See the Links in the Right Hand Column to View JSMol movable 3D images for the Solid State Structures
of Known Cu(I) and Cu(II) complexes of these and structurally similar ligands
Ligand Structure Link to 3D Structures
Me6Trien Structures of Cu(I) and Cu(II) Complexes
of the Me6Trien Ligand
BCA






Bisquinoline






MethyCarboxylate-Bisquinoline





Why would the BCA ligand be better suited for use in a biochemical experiment
relative to the Bisquinoline or or MethylCarboxylate-Bisquinoline ligand?


Structures of Cu(I) and Cu(II) Complexes
of Ligands Related to BCA
BCS






dmp = dimethyl phenanthroline



Why would the BCS ligand be better suited for use in a biochemical experiment
relative to the dmp ligand?


Structures of Cu(I) and Cu(II) Complexes
of Ligands Related to BCS

Resources developed by Marion E. Cass, Carleton College 2015; Questions for students in red font