Visualizations for the Wilcox Group, Dartmouth College

1. The Carbonic Anhydrase Project
• Carbonic Anhydrase JSmol *
• Contrasting the Zn(II) and Ni(II) complexes of Carbonic Anhydrase JSmol *


2. The Insulin Project (* Work with Molly Carpenter)
• Human Insulin
• R₆ Hexamer of Human Insulin JSmol *
• T₆ Hexamer of Human Insulin JSmol*
• T₃R₃ Hexamer of Human Insulin JSmol
• Contrasting the R₆, T₆ and T₃R₃ Structures of Human Insulin- Viewing down the C₃ Axis JSmol *
• Contrasting the R₆, T₆ and T₃R₃ Structures of Human Insulin - Highlighting the Closed and Open Cavities for Zinc JSmol *
• Contrasting the Coordination Sphere for Zn in R₆and T₆ Human Insulin JSmol *
3. The Metallochaperone Project
• Cu(I) and Cu(II) Structures of the Me₆Trien Ligand
• Cu(I) and Cu(II) Structures of the BCA and Related Biquinolinyl Ligand
• Cu(I) and Cu(II) Structures of Ligands Related to BCS


4. The MerB Project (*work with Michael Stephenson)
• Mercury Bound to the MerB Protein JSmol *


5. The Coordination Coupled Deprotonation (Zinc Binding) Switches
• QPH Structures
• QIH-Me Structures


6. The Azurin Project (* Work with Molly Croteau)
• Azurin from Pseudomonas aeruginosa, from Canters, structure 5AZU
• Copper Center in Azurin from Pseudomonas aeruginosa Cu(II) 5AZU and Cu(I) 15EZ
• MOs in Models for the Cu(II) and CU(I) Centers in Azurin from Pseudomonas aeruginosa


7. The Cu-Zn-SOD1 Project (*Work with Teddy Press)
• Oxidized form of the Full Human Cu-Zn-SOD1 Protein A Nonamer of Dimers (PDB 1HL5)
• Oxidized form of Cu-Zn-SOD1, Biological Assembly 1 - One Dimer (PDB 1HL5)
• Reduced form of Cu-Zn-SOD1, Biological Assembly 1 - One Dimer (PDB 1PU0)
• Mutant H43R of Cu-Zn-SOD1, Reduced Form, Biological Assembly 1 - One Dimer (PDB 1PTZ)


8. The Albumin Project
• Bovine Serum Albumin
• Bovine Serum Albumin - One Molecule
• Copper Binding Site -Gly-Gly-His


9. Zinc Finger Proteins
• Myelin Transcription Factor
10. For Chem 263
• Bovine Cytochrome C Oxidase
• One half of the PSII Protein conglomerate
• One half the PSII Protein conglomerate simplified
• The full PSII Protein conglomerate
11. Group Meeting 1-31-17 Metallo-Β-Lactamase Enzymes
• Binuclear Zinc Β-Lactamase from BcII